Abstract
This study aimed to characterize the phytochemical composition, as well as antioxidant and antimicrobial activities of Tunisian <i>Caulerpa prolifera</i> extracts using two different extraction methods. The total phenol, flavonoid, and condensed tannin contents of <i>C. prolifera</i> extract obtained by successive extraction were lower (1.57 mg EAG/g, 1.45 mg C/g and 2 mg C/g, respectively) than those obtained by maceration (3.67 mg GAE/g, 1.93 mg C/g and 3.50 mg C/g, respectively). <i>Caulerpa prolifera </i>extracts obtained by the two extraction methods were inactive using DPPH activity. A decrease of antioxidant activity was found by using reducing power (IC<sub>50</sub> varied from 1.72 to 6.97 mg/mL) and &beta;-carotene bleaching (IC<sub>50</sub> varied from 3.42 to 5.66 mg/mL) assays after fractionation. However, there was an increase in the antioxidant activity following the chelating power assay with IC<sub>50</sub> varying between 6.91 to 3.44 mg/mL. <i>Caulerpa prolifera </i>extracts obtained by successive extraction had the greatest antimicrobial activities against all tested strains (IZ &#61; 2-9 mm) when compared to those obtained by maceration.
Published Version
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