Abstract
Objective To investigate the effect of comprehensive nursing intervention on the effect of CT-guided intravenous thrombolytic therapy for acute cerebral infarction. Methods 99 patients with acute cerebral infarction in the internal carotid artery system who were hospitalized in our department from December 2019 to December 2020 with an onset of 3–9 h were selected and randomly divided into two groups. All patients underwent multimode CT examinations and received rt-PA thrombolytic therapy. 52 patients with conventional care were included in the control group, and 47 patients with comprehensive nursing intervention were included in the observation group. The influence characteristics, Barthel score, serum MMP-9 level, and NIHSS score were compared between the two groups. Results After the comprehensive nursing intervention, the total efficiency, total satisfaction, psychological status, and Barthel score of the observation group were significantly higher than those of the control group (P < 0.05). The serum MMP-9 level and NIHSS score were significantly lower than those of the control group (P < 0.05). Conclusion The use of comprehensive nursing interventions in the CT-guided intravenous thrombolysis treatment of ACI patients reduced the degree of neurological impairment, improved the therapeutic effect, increased nursing satisfaction, and enabled better control of the condition of patients with cerebral infarction, which is worth promoting research.
Highlights
Acute cerebral infarction (ACI) is caused by stenosis of blood vessels in the neck or intracranial. ere are many inducing factors, most of which are due to atherosclerosis of the aorta
Low tissue density was observed on NCCT in 8 patients (8.08%), which was the highest proportion of early ischemic changes, while middle cerebral artery high density was the rarest sign of early ischemia
Acute cerebral infarction is a more serious cerebrovascular disease, and patients are only able to move off the floor after a long period of recovery training after treatment, with a poor quality of life
Summary
Acute cerebral infarction (ACI) is caused by stenosis of blood vessels in the neck or intracranial. ere are many inducing factors, most of which are due to atherosclerosis of the aorta. Thrombolysis is the only treatment for acute cerebral infarction that has been proven to be the most effective by evidence-based medicine [8, 9]. Strbian et al showed that early thrombolysis was effective in reducing the disability and mortality rates of patients with ischemic stroke, and the earlier the patients received thrombolysis, the earlier the neurological recovery and better the prognosis [10]. Only 3–5% of patients with acute cerebral infarction receive intravenous thrombolysis, and many patients are lost to thrombolysis because the time of onset is unclear or the conventional time limit for thrombolysis is exceeded [11].
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