Effect of Cognitive Behavioral Therapy combined Anti-anxiety drou On Preliminary Hypertension Patients

Abstract

Objective To evaluate the curative effect of combined cognitive behaviioral therapy with alprazolam anti-anxiety. on patients with preliminary hypertemsion. Methods After evaluating by self-rating anxiety scale (SAS) ,60 outpatients with preliminary hypertension were randomly divided into A and B groups. The A group (n = 29) were accepted the combined cognitive behavioral therapy with alprazolam anti-anxiety for 8 weeks at the basis with medication, the B group ( n = 31 ) given rontine medication only. Meantimes, fifteen healthy volunteers who matched with age and sex were selected as the normal control group ( C group ). The blood pressure of all the subjects were recorded at the begin and after eight-weeks therapy,and the levels of plasma von willebrand factor (VWF) and serum high-sensitive reaction protein(hs-CRP) were measured respectively. The evaluating by self-rating anxiety scale (SAS) were performed in the A and B groups,before and after the treatment at the same time. Results The patients with preliminary hypertension have higher SAS score as well as the levels of plasma VWF and serum hs-CRP. After psychotherapy,in A group,the SAS score,the levels of VWF and serum hs-CRP, and the blood pressure were significantly decreased( P < 0. 01 ),compared with those in B group, however, were still significantly higher than those of C group( P < 0. 01 ). Conclusion The patients with preliminary hypertension showed some-degrees anxious emotion. By combined cognitive behavioral therapy with alprazolam anti-anxiety,we could not only more positively control the patients, blood pressure,but also improve the patients emotion states,as well as decrease the levels of VWF and hs-CRP. Key words: Preliminary hypertension; Cognitive behavioral therapy; Anti-anxiety; Therapy