Abstract
Background: The vitality of the pulp must be protected because the pulp contains fibers, cells, and various structures. Pulp vitality can be maintained by pulp capping to stimulate the formation of reparative dentin. The material commonly used for pulp capping is calcium hydroxide. Calcium hydroxide has the disadvantage of causing inflammation and necrosis of the pulp surface. To compensate that, propolis is added because it has the ability as an anti-inflammatory. Purpose: To analyze the increase in the number of fibroblast cells and angiogenesis in the pulp after the application of combination of Calcium hydroxide-propolis compared to the application of Calcium hydroxide.. Methods: This study used 30 samples of wistar rats which were preparated until perforation and then divided into 3 groups. The first group continued with filling with cention, the second group continued with application of calcium hydroxide and filled with cention, and the third group continued with the application of combination of calcium hydroxide and propolis and then being filledwith cention. fibroblast cells and angiogenesis is calculated histopathologically by using compound light microscopeon the 7th day with 400x magnification.Results:Based on the results of the study found a significant difference between the calcium hydroxide group and the calcium hydroxide-propolis group. Increased numbers of fibroblasts and angiogenesis indicate a faster inflammatory process that affects the acceleration of wound healingConclusion: More number of fibroblasts and angiognesis cells found in the pulp after the application of a combination of Calcium hydroxide-propolis compared to the application of Calcium hydroxide
Highlights
The dental health of the Indonesian people needs to be maitained
In the normality test it is found that the data is not normally distributed, so the non-parametric test is done using the Kruskal-Wallis test in each group to find out whether there is a significant difference between the treatment groups
Based on the results of the study there was a significant difference between the number of fibroblast cells in the control group, the treatment group with calcium hydroxide, the treatment group with a combination of calcium hydroxide and propolis based on the Krusskal Wallis test with p = 0.000 indicating that there were differences between the study groups
Summary
The dental health of the Indonesian people needs to be maitained. Dental and oral diseases are in the top ten most diseases spread in various regions[1]. Calcium hydroxide can kill microorganisms because it has a high pH This condition can stimulate the formation of fibroblasts. Calcium hydroxide has deficiencies that cause inflammation and necrosis of the surface of the pulp after the pulp capping, has high solubility, may undergo degradation, forming a brittle dentin bridge, and has low mechanical barriers and may be able to cause microfiltration and causing failure of treatment 4. Propolis is a resin material collected by honey bees from various plants that have been used as anti-inflammatory drugs. Based on the background behind it, more research is needed on the effectiveness of the administration of a combination of calcium hydroxide and propolis as an antiinflammatory in terms of the number of cell fibroblasts and angiogenesis in the tissue of the pulp of Wistar rat’s teeth
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