Abstract
Transport of solutes through membrane channels produces additional noise in the channel ion current because the number of solute molecules in the channel fluctuates. We obtain a general expression for the power spectral density of these fluctuations in a cylindrical channel in the presence of a binding site of arbitrary strength. The expression shows how the spectral density transforms from that in the case of no-binding to the Lorentzian spectral density corresponding to the strong-binding limit. Brownian dynamics simulations confirm our analytical results.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.