Abstract
Editorial: Optogenetic Tools in the Molecular Spotlight.
Highlights
Specialty section: This article was submitted to Biophysics, a section of the journal Frontiers in Molecular Biosciences
Photosensory receptors have been in the center of vision research and photobiology since the discovery of rhodopsin in 1876 by Franz Boll
Combined with techniques capable of molecular resolution such time-resolved experiments provide dynamic molecular information on the underlying mechanisms of photosensory and general signal transduction, and will enable us to identify structure/function relations and design principles of biological sensor/effector complexes. This knowledge will allow us to rationally design novel light-responsive tools with customized properties for application in optogenetics and synthetic biology. This ebook features research articles and reviews covering the most prominent photosensory modules applied in optogenetics, as represented by flavin based photoreceptors (LOV and BLUF), phytochromes and microbial opsins
Summary
Specialty section: This article was submitted to Biophysics, a section of the journal Frontiers in Molecular Biosciences. With the nowadays available information on the corresponding genes, proteins and the vast access to (meta-) genomic data as well as sophisticated methods in molecular biology and genome engineering the photoreceptor principle of transforming light into biological information is exploited in many different fields of research.
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