Abstract
AIM. Study of the dynamics of bone metabolism in the treatment of generalized periodontitis.MATERIALS AND METHODS. 60 patients with chronic generalized periodontitis of moderate to severe severity were examined and treated. A group of 15 healthy individuals without periodontal disease served as a control group. To assess the dynamics of bone formation, blood parameters were measured for bone metabolism: osteocalcin levels, alkaline phosphatase levels, and β-CrossLaps levels. Densitometry of the proximal femoral and lumbar spine regions was also performed.RESULTS. The study revealed increased bone metabolism compared with the control group, an increase in bone metabolism activity was found 3 months after treatment of patients with chronic generalized periodontitis, and after 12 months the values of the studied parameters did not differ from the control group.CONCLUSIONS. Thus, when treating generalized periodontitis, it is necessary to use a treatment regimen that takes into account the individual mineral metabolism of the patient’s bone tissue.
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