Does Orthodontic Treatment induce Erythema Multiforme

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Oral erythema multiforme (EM) is considered as a third category of EM other than EM minor and major. Patients present with oral and lip ulcerations typical of EM but without any skin target lesions. It has been reported that primary attacks of oral EM is confined to the oral mucosa but the subsequent attacks can produce more severe forms of EM involving the skin. Hence, it is important to identify and distinguish them from other ulcerative disorders involving oral cavity for early management. This article reports a case of oral EM that presented with oral and lip ulcerations typical of EM without any skin lesions during first phase of orthodontic treatment and highlights the importance of early diagnosis and proper management.