Abstract
Genetic polymorphism of six red cell enzymes, namely, acid phosphatase (AcP), 6-phosphogluconate dehydrogenase (6-PGD), phosphoglucomutase (PGM), adenosine deaminase (ADA), phosphohexose isomerase (PHI) and adenylate kinase (AK) have been studied by the method of starch gel electrophoresis. The red cell samples were taken from unrelated individuals in three prefectures in the district of Tohoku, nothern part of Japan. In the present samples heterozygosity of variants at 6-PGD, PGM and PHI locus has a relatively high degree compared with Caucasian, while the gene frequencies of ADA2 appears to be somewhat lower than those observed in Caucasian. Pc gene of acid phosphatase and any sample showing a deviating pattern from the common type AK-1 were not observed in the present samples. These results are in good agreement with those reported so far for Japanese populations. No heterogeneity was observed for each of the six enzyme systems among sample groups for three prefectures.
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