Distribution of pathogens in complicated urinary tract infection and drug resistance of Gram-negative bacteria

Abstract

Objective To investigate the distribution of pathogens in complex urinary tract infection and the drug resistance of Gram-negative in the main pathogens in Shiyan area. Methods From January 2014 to January 2017, 195 patients with complicated urinary tract infection were enrolled in the hospital, and urine was collected in the middle stage. Urine culture and drug sensitivity test were carried out. The results were analyzed by WHONET 3.7 monitoring network of drug resistance. Results Of the 195 samples, 146 strains were isolated, 98 strains were Gram-negative strains (67.12%), 42 strains were Gram-positive cocci (28.77%) and 6 strains(4.11%) were anaerobic bacteria. Gram-negative bacilli were mainly Escherichia coli (29.45%), Pseudomonas aeruginosa (13.70%) had an upward trend, and the singular deformed rod (9.59%) was the third. These three Gram-negative bacteria resistance to piperacillin, cefoperazone sulbactam, levofloxacin and other drugs were more than 40%, resistance to imipenem, amikacin was less than 10% and drug resistance of complex urinary tract infection was serious. Conclusions The pathogens of complex urinary tract infection are mainly Gram-negative bacilli Escherichia coli, and the drug resistance is serious, it need to be closely combined with the results of drug susceptibility combined with anti-infective treatment to reduce the emergence of drug-resistant strains. Key words: Urinary Tract Infections; Gram-Negative Facultatively Anaerobic Rods; Drug Tolerance