Abstract
A total of 300 Japanese people from 2 wk to 98 yr of age were tested for immunoglobulin (Ig) G and E antibodies to salivary gland extracts of Aedes albopictus (Skuse) mosquitoes by an enzyme-linked immunosorbent assay. Almost all had IgG antibodies. The mean IgG antibody levels increased with age up to 2 yr and then leveled off, indicating a relatively frequent exposure to Aedes-mosquito bites. Distribution patterns of IgE antibody levels were similar among all age groups. The antibody status involved in mosquito allergy, especially in the five-stage sequence of skin reactivity, is discussed.
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