Distribution and Histopathological Evaluation of Eyelid, Conjunctival and Orbital Tumours

Abstract

Introduction: Ocular neoplasm being the most important cause of morbidity and mortality, early diagnosis and detection of the pathology is crucial for proper treatment and better prognosis. In clinical practice, eye Tumours and Tumour-like lesions can be classified into extra- and intra-ocular. Benign growth of eyelid includes xanthelasma, molluscum, warts, naevus, angioma and other tumers common to skin and cutaneous glands. Present study conducted with following Objectives: 1. To highlight the benign and malignant Tumours of eyelid, conjunctiva and orbit for early diagnosis and management. 2. Histopathological analysis to establish the type and subtype of benign and malignant Tumours. Methodology: This present study was a hospital based, longitudinal study conducted between August 2012 to August 2014. Patients with benign and malignant Tumours of eyelid, conjunctiva and orbit were included in the study and those who had Infective, inflammatory and traumatic lesions of eyelids, conjunctiva and orbit were excluded from study. Results: The study comprised 36 cases, out of them 19 subject had Eyelid, 9 Conjunctival and 8 Orbital Tumours. Among 19 eyelid Tumours, we found 17 Benign Tumours and 2 Malignant Tumours. Most common benign Tumour of eyelid seen in our study was Nevus (7 cases) followed by epidermoid cyst (5 cases), Papilloma(3 cases), xanthelasma(1 case), keratin cyst(1 case). Most common benign tumour of conjunctiva seen in our study was Nevus (4 cases), followed by dermolipoma (2 cases), papilloma (1 case) and dermoid cyst (1 case).All 4 Nevus cases were melanocytic nevus type. Most common benign Tumour of orbit in our study was Hemangioma(3 cases), followed by neurofibroma(2 cases) and Dermoid cyst(2 cases). Conclusion: The clinical evaluation and histopathological examination of the ocular Tumours has immense role in classifying the Tumours, establishing the final diagnosis and also in planning the most effective treatment modalities to reduce the morbidity and mortality to the possible extent.