Abstract
Histoplasmosis, caused by the dimorphic fungus Histoplasma capsulatum, is an endemic disease in North and Central America, but rare in Taiwan. In most healthy individuals, histoplasmosis is asymptomatic and usually discovered incidentally during evaluation for other conditions. The initial infection with H. capsulatum is pulmonary. Widespread disseminated histoplasmosis occurs in immunocompromised patients with defective T-cell immunity. This case report describes an initially immunocompetent patient who presented with hemolytic anemia and asymptomatic lung consolidation. After being treated with prednisolone for 6 months, she progressed to a fatal disseminated histoplasmosis as diagnosed by bone marrow pathology and culture.
Published Version
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