Abstract
Abstract The antigenicities of yeast phase suspensions derived from strains of Histoplasma capsulatum were determined through titrations of hyperimmunized rabbit sera and of human sera from culturally proved and presumptive cases of histoplasmosis. Considerable variations in reactivities were noted and the results obtained were similar with human or rabbit sera. Hyperimmune rabbit sera therefore may be used as control sera in the determination of the optimum yeast phase antigen dilutions. To assure the selection of potent yeast phase antigens for use in complement fixation tests a large series of antigens derived from different strains of H. capsulatum should be screened.
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