Abstract

Diclofenac is a non-steroidal anti-inflammatory drug, which has been on the market for many years. During its clinical use, it has been confirmed as an effective analgesic for the treatment of acute post-traumatic pain, postoperative pain, and chronic pain conditions such as chronic back pain and rheumatoid arthritis. In addition to its analgesic effects, it has also been confirmed as an anti-inflammatory drug and antipyretic. Diclofenac is available on the market in various formulations that allow for its systemic use intravenously, intramuscularly, orally, rectally, or topically on the skin and mucous membranes. This review article aims to present the main methods of diclofenac administration and the results of some studies comparing its efficacy with other non-steroidal anti-inflammatory drugs. The most common side effects and strategies for avoiding them are also presented.

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