Abstract
Background: Early disturbances of carbohydrate metabolism are an independent risk factor of development of cardiovascular diseases. Objective: The diastolic dysfunction and left ventricle remodeling depending on presence of impaired fasting glucose were examined. Methods: The characteristics of heart remodeling and fasting glucose of capillary blood were studied in 85 men aged 30 to 63 years without coronary heart disease. Results: In male patients with impaired fasting glucose in comparison of persons with level of glucose less than 5.6 mM/l, more pronounced diastolic dysfunction and left ventricle remodeling associated with more often presence III degree of peripheral obesity. Conclusion: Impaired fasting glucose in men increases probability of development of heart remodeling.
Highlights
The difficulty of medical and economic consequences does prevention of type 2 diabetes mellitus by one of important directions in health care [1]
For increase in efficiency of prevention of type 2 diabetes much attention is paid to timely revealing of early disturbances of carbohydrate metabolism, the presence of which is accompanied by an increase in the risk of death from cardiovascular disease [2]
For diagnostics diastolic dysfunction we studied early ventricular filling (E-wave); late ventricular filling (A-wave); E/A ratio; isovolumic relaxation time (IVRT); E-wave peak velocity; E-wave deceleration time (EDT); A-wave duration
Summary
The difficulty of medical and economic consequences does prevention of type 2 diabetes mellitus by one of important directions in health care [1]. For increase in efficiency of prevention of type 2 diabetes much attention is paid to timely revealing of early disturbances of carbohydrate metabolism, the presence of which is accompanied by an increase in the risk of death from cardiovascular disease [2]. (2015) Diastolic Dysfunction and Left Ventricle Remodeling in Men with Impaired Fasting Glucose. Disturbances of carbohydrate metabolism are an independent risk factor of development of cardiovascular diseases. Objective: The diastolic dysfunction and left ventricle remodeling depending on presence of impaired fasting glucose were examined. Results: In male patients with impaired fasting glucose in comparison of persons with level of glucose less than 5.6 mM/l, more pronounced diastolic dysfunction and left ventricle remodeling associated with more often presence III degree of peripheral obesity.
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