Abstract
Diagnostic Molecular Microbiology and its applications: Current and Future Perspectives
Highlights
Infectious disease is the main cause of mortality and morbidity worldwide
The era of antibiotic, antiviral, antimycotic, and antiparasitic has led to alleviation from these infectious agents, the rampant use of these agents has led to the emergence of multi drug resistant (MDR) pathogens which if not diagnosed and contained early, could spread to large geographical areas [2]
Due to the above reasons, there is a large scope for molecular biology procedures in the diagnostic clinical microbiology laboratory
Summary
The different types of infection caused by various types of pathogens including bacteria, viruses, parasites and fungi are ever increasing [1]. It is due molecular testing that the phenotypes exhibited by a pathogen can be genetically confirmed [4] It ensures rapid diagnosis at a cost effective price, increasing the diagnostic arsenal for pathogen identification. This review enlists the various types of molecular typing methods which have been inculcated in molecular microbiology diagnostic labs It describes the need for more advanced molecular methods for increasing the sensitivity and specificity of diagnosis and the routine protocols for various bacterial, viral, fungal, and parasites that have been already standardised at the genus and species levels with a briefing on sample acceptance and rejection criteria for the enlisted pathogens
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