Abstract

Efficacy of azithromycin versus other antibiotics in the treatment of patients with upper respiratory tract infections

Highlights

  • Upper respiratory tract infections (URTIs) are one of the most common problems found in pediatric emergency care services, resulting in significant morbidity worldwide

  • In order to carry out this study, data were collected from patients seen in a specialized emergency room with a clinical history of URTI and failure of first choice antimicrobial therapy from 2018 to 2020 under an established criterion; Results: there was a considerable prevalence of patients with refractory URI who used azithromycin (44%) alone and amoxicillin (15%), mainly

  • We have confirmed the ineffectiveness of using azithromycin as the first choice for the treatment of URTI

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Summary

Introduction

Upper respiratory tract infections (URTIs) are one of the most common problems found in pediatric emergency care services, resulting in significant morbidity worldwide. URTIs are the most common cause of children treated for acute respiratory infection. The difficulties observed in clinical practice in relation to the differential and etiological diagnosis of certain URTIs and the use, often abusive, of antimicrobials [1]. They are a very frequent cause of recourse to Primary Health Care (PHC), with a frequency of 11 to 33% of URTIs being reported in all reasons for consulting General and Family Medicine [2]. The inflammation cascade initiated by nasal epithelial cells will lead to damage by infiltrating cells, causing edema, engorgement, fluid leakage, mucus production and sinus obstruction in the process, leading to acute rhinosinusitis (ARS) [3]

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