Development of the composіtіon and technology of the herbal mixture with the cerebroprotectіve actіon

Abstract

Aіm. To determine the prospects for using the plant raw material for the creation of herbal medicines with the cerebroprotective effect, as well as to develop the composition and technology of a new medicine of natural origin. Materіals and methods. The study objects were black horehound (Ballota nigra L.) herb, white dead nettle (Lamium album L.) herb, and Austrian wormwood (Artemisia austriaca) herb. Experimental studies were conducted using modern physical, physicochemical, pharmacotechnological, and mathematical methods of analysis. Results and dіscussіon. Based on the analysis of scientific sources on the situation with cerebrovascular diseases (CVD) and the range of drugs for their treatment, it has been proven that to improve the quality of therapy, it is rational to conduct a complex pharmacotherapy with the use of herbal medicines. We have proposed a new drug with the cerebroprotective action based on the plant raw material. The medicinal product was obtained in the form of the herbal mixture, which included black horehound herb, white dead nettle herb, and Austrian wormwood herb. The rational technology of the drug has been theoretically and experimentally substantiated. A block diagram of the herbal mixture has been developed, and the critical parameters of its production have been determined. The pharmacotechnological studies of the plant raw material and the drug obtained have been conducted. Conclusіons. Based on the results of the work conducted, the data scientific sources on the spread of CVD have been analyzed and summarized; the expediency of using the plant raw material in medicines for a complex pharmacotherapy of CVD has been proven; the composition and technology of the drug from black horehound herb, white dead nettle herb, and Austrian wormwood herb in the form of the herbal mixture with the cerebroprotective action for internal use have been developed.