Development of Technology for Obtaining Herbal Extracts of Adonis Vernalis

Abstract

This paper reveals the relevance of developing a technology for obtaining extracts of medicinal plant raw materials Adonis vernalis for its use as an individual drug or as part of a complex drug. Optimal indicators of extraction of biologically active substances of Adonis vernalis that affect the technological process, namely the particle size, the type of extractant, the size of the hydraulic module, and the extraction method, are established. Considering energy-intensive, technological, and design factors, the best option for the process to obtain the maximum yield of the target component was chosen, namely, the circulating extraction of Adonis vernalis flavonoids. Kinetic regularities of the extraction process are determined. Based on the selected mathematical model, it was checked for adequacy. Extraction constants are determined. The issues of selecting technological equipment for obtaining this extract with a high content of the target component are considered. The optimal parameters of the Extraction mode of Adonis vernalis herb are established: extractant – 70% Ethanol, the degree of grinding of raw materials – 1.0–2.0 mm, the ratio of raw materials-extractant – 1:15, the extraction method – circulation. Also, this development will expand the range of raw materials for drugs that have antioxidant activity.