Abstract
Human papillomavirus (HPV) infection is one of the common sexually transmitted infections worldwide. As is known, persistent high-risk HPV infection is closely related with cervical cancer and precancerous lesions. HPV detection is widely used in the natural history and etiological study of HPV-related diseases. HPV detection or type identification is significant to screening, early diagnosis, treatment and prognosis evaluation of HPV-related diseases. With the development of molecular biology and immunology, biomarker detection has gradually become the researching hotspot. The development status and research progress of HPV detection are reviewed in this article. Key words: Papillomaviridae; Nucleic acid hybridization; PCR; Oncoprotein; Methylation
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