Abstract
In this work, a graphene oxide-based nano-delivery system was designed for a sustainable release of caffeic acid. The graphene oxide (GO) nanocarrier was prepared by employing the modified Hummers method. Furthermore, the natural chemotherapeutic agent caffeic acid with different weight proportions was successfully loaded on GO. The 2D nano-morphology, structure and surface chemistry of GO, GO-CA nanocomposite were further investigated via various characterization techniques. The maximum loading efficiency of GO was found as 40 %. A sustainable release of CA from GO-CA nanocomposite was observed with 66 % as the maximum amount of release in 72 h and followed the pseudo-second-order kinetic model.
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