Development of an ointment for burns based in dry extract of the seaweed Fucus spiralis

Abstract

Event Abstract Back to Event Development of an ointment for burns based in dry extract of the seaweed Fucus spiralis Gonçalo M. Bernardo1, Gonçalo Castro1, Marcia S. Santos1, Maria M. Sampaio1 and Clélia N. Afonso1* 1 School of Tourism and Maritime Technology, Marine Resources Research Group (GIRM), Polytechnic Institute of Leiria, Portugal The Fucus spiralis is a brown seaweed found on the Portuguese coast used as wound healing in traditional medicine were their antioxidant, immunostimulant, anticoagulant, antibacterial properties and also remineralizing, smoothing, moisturizing capacities and anti-tumor action were studied with proved results. These seaweed are one of the several described in the European Pharmacopoeia, making F.spiralis a seaweed with great potential for the development of new drugs and/or pharmaceuticals. The objective of this project was to formulate an ointment with F. spiralis dry extracts using vaseline as a base for the treatment of burns. Fucus spiralis was collected on the coast of Peniche (west coast of Portugal), washed, sorted, lyophilized and crushed for the dry extract preparation. The ash (g/g) and iodine (%) content in F. spiralis were determined. The ointment was prepared and homogenized with three concentrations of dry extract (1%, 2% and 5%) and were analyzed over time in parallel with the observation of the physical, chemical, organoleptic and rheological characteristics. The results showed that the F. spiralis presented a iodine content of 0,0076%, a low concentration in comparison with the Farmacopeia europea directives. The ointment prepared is a non-Newtonian fluid, and the absorption spectrum in ultraviolet light (UV) detected that it behaves as UVB and UVC blocker, despite of not having the same effect on UVA radiation. With these results and the many properties of Fucus spiralis we conclude that the ointment with dry extract of F. spiralis with the three concentrations of dry extract established is likely to have a great potential in the area of pharmaceutical and medicine, especially for burns application or other skins disorders. Acknowledgements The first two authors contributed equally to this work. The authors wish to thank all the colleagues from ESTM who assisted in field and laboratory work in some steps of this work. Keywords: Fucus spiralis, ointment, Burns, seaweed extract, Brown algae Conference: IMMR | International Meeting on Marine Research 2014, Peniche, Portugal, 10 Jul - 11 Jul, 2014. Presentation Type: Poster Presentation Topic: BLUE BIOTECH Citation: Bernardo GM, Castro G, Santos MS, Sampaio MM and Afonso CN (2014). Development of an ointment for burns based in dry extract of the seaweed Fucus spiralis. Front. Mar. Sci. Conference Abstract: IMMR | International Meeting on Marine Research 2014. doi: 10.3389/conf.fmars.2014.02.00002 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 23 May 2014; Published Online: 18 Jul 2014. * Correspondence: Prof. Clélia N Afonso, School of Tourism and Maritime Technology, Marine Resources Research Group (GIRM), Polytechnic Institute of Leiria, Peniche, 2520-641, Portugal, clelia@ipleiria.pt Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Gonçalo M Bernardo Gonçalo Castro Marcia S Santos Maria M Sampaio Clélia N Afonso Google Gonçalo M Bernardo Gonçalo Castro Marcia S Santos Maria M Sampaio Clélia N Afonso Google Scholar Gonçalo M Bernardo Gonçalo Castro Marcia S Santos Maria M Sampaio Clélia N Afonso PubMed Gonçalo M Bernardo Gonçalo Castro Marcia S Santos Maria M Sampaio Clélia N Afonso Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.