Development of a Portable Electrical Impedance Tomography Device for Online Thrombus Detection in Extracorporeal-Circulation Equipment

Abstract

A portable Electrical Impedance Tomography (EIT) device has been developed for online thrombus detection in extracorporeal-circulation equipment. For the portable EIT device, circuits of multiplexer module are designed to expend channels, pipeline processing mechanism is introduced to increase processing speed, and data acquisition rate reaches 50 Frames Per Second (FPS) and the online tomography rate reaches 40 FPS with 8-electrode sensor. To test the characteristics of the proposed EIT device, a series of experiments are conducted. Firstly, small sensors with different size and plastic phantoms are used to test the static properties of the device. Testing results show that the quality of the reconstructed images is related to the diameter of sensor, and Image Correlation (IC) reaches 0.75 when diameter of sensor is 30 mm. Secondly, swine blood is used for making thrombus to verify the EIT device's image reconstruction ability of thrombus in stationary conditions instead of human blood. Experiments show that the reconstructed image error is 8.07% when diameter of the sensor is 10 mm, and it reduces to 1.49% when diameter is 30 mm. Finally, experiments are conducted to measure the position of flowing thrombus. Euclidean distance between voltage data is used to judge the occurrence of thrombus. Experimental results indicate that thrombus is clearly distinguished from the background solution in fluids. As a conclusion, the proposed EIT device is of great significance for online thrombus detection in extracorporeal-circulation system.