Abstract

Probes made by inter- Alu-PCR from an interspecific somatic cell hybrid containing only the distal half of the 9q as its only human genomic content when used for fluorescence in situ hybridization (FISH) on the cells of a chronic myelogenous leukemia (CML) patient detected involvement of chromosome 9 in a complex translocation that was not observed by standard G-band cytogenetics.

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