Detection and diagnositic value of serum procalciton in and C-reacti protein in children with nervous system infection

Abstract

Objective To investigate the clinical value of serum procalcitonin(PCT) and C-reactive protein (CRP) piagnosis of in children with acute bacterial meningitis and virus meningitis.Methods The serum PCT and CRP levels in 30 children with acute bacterial meningitis and 30 children with virus meningitis were measured by electrochemiluminescence immune assay(ECLIA) and compared with 30 healthy children(control group).Results The level of serum PCT in bacterial meningitis group was significantly higher than that in control group and viral meningitis group(t =7.67,5.67,P ＜ 0.01 ).The level of CRP in bacterial meningitis group and viral meningitis group was higher than that in control group ( t =2.52,2.47,P ＜ 0.05 ),but no significant difference between bacterial meningitis group and viral meningitis group (t =1.87,P ＞ 0.05 ).Conclusion PCT and CRP had clinical application value in the differential diagnosis of bacterial and viral meningitis. Key words: Procalcitonin; C-reactive protein; Meningitis