Design of Sixteen-Input Priority Encoder with DNA Nano Switches

Abstract

With the application of DNA computing in more and more fields, the tasks are becoming more and more complex, and the scale of DNA circuits is gradually increasing. However, the current investigation of largescale circuits of DNA molecules is still a challenge. So it is crucial to optimize the performance of large-scale DNA circuits. In this paper, a large-scale digital logic circuit 16-Input-5-Output Priority Encoder is realized by using the DNA nano switches for the first time. The simulation of the 16-Input-5-Output Priority Encoder circuit shows that this method solves the problems of NOT gate instability and optimizes the DNA circuit in terms of reaction time, circuit complexity, and experimental difficulty. This paper proves the feasibility and superiority of using DNA nano switches to realize large-scale circuits, provides a new idea for realizing large-scale DNA circuits, and brings new development for the application of DNA circuits in biosensor, DNA complex computing and other fields.