Abstract

In this project we design and study a differential phase surface plasmon resonance sensor combining with microfluidic technology. The differential phase Surface Plasmon Resonance (SPR) sensor is constructed by applying the Kretschman plasmon excitation structure and combing with interference spectroscopy. Through making use of simulation and experimental method, the principle of SPR sensor is theoretically and experimentally studied. In this project, we apply the SPR sensor in testing urea solution with varying weight concentration. Through the results, it can be observed that the plasma resonance absorption ranges from 640 nm to 840 nm and its detection limits can reach 0.0004 RIU. Due to its tunable plasma absorption and lower detection limits, the microfluidic differential phase surface plasmon resonance sensor illustrates a promising future in chemistry, physics and biology.

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