Abstract

Different designs of three-dimensional (3D) structures have gained increasingly significant in bone tissue engineering. For scaffolds, having appropriate porosity and adequate mechanical properties is crucial. The porosity and mechanical properties of scaffolds are higly influenced by their 3D modeled design. By evaluating the mechanical properties of scaffolds with various designs, it can be confirmed that they could serve as an important platform for the regeneration of damaged bone tissue. In this study, a diverse range of unit cells and lattice structures featuring different pore structures of polylactic acid (PLA)/hydroxyapatite (HA) based scaffolds were modeled and designed. Structural analyses of the designed models were conducted in a simulation environment and their mechanical properties were compared with similar studies. The results suggest that PLA/HA-based scaffolds with different designs hold high potential for applications in bone tissue engineering.

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