Abstract
We developed lipid nanoparticles for effective visualization of reactive oxygen species (ROS) in damaged hepatocytes. These nanoparticles contain ROS - sensor: 1) HyPer – plasmid DNA encoded the same protein that is sensitive to the hydrogen peroxide or 2) hydrocyanine (leuco-form of cyanine) 5). The physicochemical characterization of the obtained particles was carried out, as well as their efficacy in vitro and in vivo was evaluated.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have