Abstract
Abstract It is well known that mental stress often induces gastrointestinal (GI) symptoms, such as abdominal pain, nausea and diarrhea. Irritable bowel syndrome (IBS) is one of the most common diseases, characterized by abdominal pain
Highlights
In recent years, a large number of people in advanced countries are exposed to various psychosocial stressors in their complicated daily lives
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal (GI) disorder, defined as a chronic continuous or remittent disorder characterized by abdominal discomfort or pain combined with altered bowel habits, diarrhea, constipation or alteration of both, and associated with stress, depression, anxiety, tension, or previous intestinal infection [1]
Whole trend of high-frequency component (HF) amplitude seems lower in GI subjects than in controls, though there was no significant interaction or main effect of group in the whole trend (Figure 2)
Summary
A large number of people in advanced countries are exposed to various psychosocial stressors in their complicated daily lives. These stressors are believed to contribute highly to the pathogenesis and development of some psychosomatic disorders. Abnormal brain-gut interaction [2,3], altered emotional processing [4], gastrointestinal motility and secretion disorder [5,6,7], autonomic nervous dysfunction [8,9,10,11], visceral hypersensitivity [12,13,14], or altered CRF signaling [15,16,17], which are supposed to be at least partially attributable to some kind of stress, are considered to play an important role in the pathogenesis of IBS.
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