Abstract

Electrocardiography (ECG or EKG) is a fundamental tool in cardiovascular diagnosis, relying on the accurate identification of the isoelectric line as a reference point. However, the definition of the isoelectric line has encountered controversies and nuances, particularly regarding its association with the TP segment, the ST segment under specific conditions, and the PQ junction in select circumstances. This comprehensive review navigates through these complexities, addressing clinical implications, methodological challenges, and potential future directions. Understanding the isoelectric line’s intricacies is essential for precise EKG interpretation and informed clinical decision-making in cardiology.

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