Deciphering the role of Andrographis paniculata in pharmaceutical field and chromatographic evaluation of Andrographis paniculata in the solution of methanol and hexane through HPTLC

Abstract

This article explores the medicinal potential of Andrographis paniculata (Kalmegh) in Ayurveda, focusing on its hepato protective and anti febrile properties. The paper emphasizes the importance of herbal medicines in primary health care due to their availability, compatibility, and affordability. Additionally, it discusses the rich herbal medicinal wealth in India and the historical significance of Ayurveda. The study delves into the pharmacological actions of Andrographis paniculata including anti-inflammatory, anti-diabetes, anti-viral, and immune stimulating pro-perties. The main objective is chromate-graphic evaluation using High-Performance Thin Layer Chromatography (HPTLC) to analyze the chemical composition of Andrographis paniculata. The HPTLC method is detailed, which is used in qualitative analysis of Andrographis paniculata. The article concludes with the qualitative analysis of Andrographis paniculata, comparing chromatograms in different solvents and wavelengths. Methanol is identified as the superior solvent providing a clearer chromatogram. Chemical constitution analysis reveals the number of visible chemicals at different wavelengths, offering insights into the herb's composition. The study provides valuable information for pharmaceutical quality control and the analysis of medicinal plant.