Phytochemically tailored zinc based ayurvedic nano-medicine: Therapeutic Importance and Prospects

Abstract

Ayurveda, a time honoured traditional system of medicines, has thrived on its profound understanding of the correlation between human body constitution and the elements of the universe. Yashad Bhasma (Zinc Oxide), a unique Ayurvedic metallic preparation, has been employed for centuries in treating various ailments, offering a holistic approach as an immune booster and a healing agent. Phytochemically tailored Zinc based herbomineral novel preparations/formulations have been explored to be an important wide spectrum therapeutic, based on blended pharmacy methods. The article introduces the concept of zinc-based Ayurvedic nano-medicine, emphasizing the therapeutic potential of zinc oxide nano-particles, an evidence based herbo-mineral formulation which has embraced reverse pharm. principles. There lies resemblance between Ayurvedic Bhasmas and chemically metal oxides, Physicochemically, Biochemically and also in-turn physiologically. The trans-formation of metallic zinc into assimilablezinc oxide as per modified Ayurvedic methodology may be of paramount significance. This conversion not only eliminates the toxicity of the metal but also enhances biocompatibility, paving the way for targeted drug delivery and medical imaging on the lines of ADMET. Furthermore, the study calls for comprehensive standardization measures, addressing qualitative and quantitative aspects. The article highlights the necessity of scientific strategies to navigate challenges in Yashad Bhasma research, ensuring its safety, quality, and medicinal efficacy by phytochemical blending. The research advocates for a harmonious blend of traditional wisdom and modern scientific rigor to propel Ayurvedic medicinal system, specifically Yashad Bhasma, into mainstream healthcare. Standardization and redesigning may emerge as the cornerstone for bridging the gap between ancient healing practices and contemporary healthcare to foster global acceptance and utilization of Ayurvedic treatments, accepted as have been realised, practiced and proved during pandemic Corona as Repurposed therapeutic strategy.