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Abstract
This research included synthesized ten new compounds (1–10) based on alkyl halides, and estimated their anti-cancer effectiveness. All prepared products are proven by Proton nuclear magnetic resonance (1H NMR) and infrared spectroscopy (IR). The anti-cancer effect of compounds 6, 9, and 10 were assessed on MCF-7 breast cancer in human cells, then WRL68 cancer cells. Compound 9 revealed to be most strong with IC50 119.2 μg/mL against MCF-7, while other compounds showed moderate anti-cancer activity. The discoveries of ponder can upgrade the understood of natural exercises of these thiols compounds.
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