Abstract
The spread of the COVID-19 pandemic posed a serious challenge for scientific and clinical medical institutions in terms of research for new multiple sclerosis (MS) treatments. In this review we discuss the associations between coronavirus infection and MS and provide data on the features of MS pathogenetic therapy during a pandemic. We also analyze the ethical aspects of clinical trials, the problems faced by researchers and patients, especially when using immunosuppressive therapy for MS. We provide examples of violations during research caused by the influence of a pandemic, as well as ways of solving them. Improving ethical standards is an essential component of ensuring the safety of MS and other immune-mediated diseases treatment.
Highlights
Распространение пандемии коронавирусной инфекции COVID-19 стало серьезным вызовом для научных и клинических медицинских учреждений при проведении исследований новых методов терапии рассеянного склероза (РС)
In this review we discuss the associations between coronavirus infection and multiple sclerosis (MS) and provide data on the features of MS pathogenetic therapy during a pandemic
We analyze the ethical aspects of clinical trials, the problems faced by researchers and patients, especially when using immunosuppressive therapy for MS
Summary
Распространение пандемии коронавирусной инфекции COVID-19 стало серьезным вызовом для научных и клинических медицинских учреждений при проведении исследований новых методов терапии рассеянного склероза (РС). Актуальные этические вопросы проведения научных клинических исследований препаратов для патогенетической терапии рассеянного склероза в условиях пандемии COVID-19.
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