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Abstract
Abstract: The current framework of cellular immunology distinguishes two large universes of immune responses – cell-mediated immunity (CMI) and humoral antibody (immunoglobulin) production. Each universe is complex and involves a variety of cells and cellular products, both specific and nonspecific. In CMI, the specific cells are thymus-derived (T) lymphocytes, which, upon interaction with antigen attached to nonspecific macrophages, become activated to produce soluble non-immunoglobulin products called lymphokines. These substances are responsible for a variety of biological processes including “delayed” inflammatory reactions, cell killing, etc. T lymphocytes appear to recognize largish antigenic determinants, but we are not sure of the chemical nature of their antigen-recognizing surface receptors.
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