Curcuma longa Aided Ag/CS Nanocomposite Coating of Surfaces as SARS-CoV-2 Contamination Minimizing Measure Towards Containment of COVID-19: a Perspective

Abstract

In the ongoing pandemic outbreak of the coronavirus disease 2019 caused by Severe Acute Respiratory Syndrome Coronavirus 2, rapid research promoting irradiation strategies to approved therapeutics and authorized immunity-boosting options for eradication of the novel coronavirus is still at a primary stage. Based on the evidence, a perspective of contamination minimizing measure is presented here, providing preventive technique through a maximized coating of surfaces with self-sterilizing antimicrobial nanocomposite material, consisting of antiviral properties to effectively combat the threat. Curcuma longa L. and polyphenolic compound curcumin present in its rhizome, since ages have been subjected to extensive antimicrobial investigations and exhibit proven antiviral activity, possessing synergism enhancement characteristic to the inhibitory effect of other antimicrobial agents. Silver nanoparticles, also considered potential tool against a variety of viruses and effectiveness of the silver/chitosan coating system is amplified in combination with adherent curcumin from Curcuma longa rhizome extract, which effectuated nanosilver generation for the approach. Nanobiotechnological synthesis of silver/chitosan nanocomposite antimicrobial surface coating, aided by Curcuma longa rhizome, chiefly consisting of curcumin. Synergistic effect of curcumin and nanosilver antiviral agents minimizing contamination. Facile coating system feasible over maximum exposed surrounding contact areas having metallic, ceramic, polymeric, wooden, etc., surface texture. The self-sterilization and unchanged function of commonly handled handles, railings, switches, touch screens, keyboards, tabletops, etc. They are imparting preventive measures to combat SARS-CoV-2 associated COVID-19 infection.