Abstract
Objective. This study aimed to evaluate the improvement and neurological function changes of patients with ischemic stroke in the posterior circulation before and after interventional therapy using magnetic resonance imaging (MRI) under genetic algorithm and compressed sensing algorithm. Methods. Thirty-six patients with posterior circulation ischemia who visited the interventional cerebrovascular disease area were included in this study. The treatment effect was observed through abnormal signal changes in the lesion area on each sequence of MRI images before and after treatment. The National Institutes of Health Stroke Scale (NIHSS) was used for the evaluation of the changes in neurological function. Results. The real data experiment results suggested that the peak signal-to-noise ratio (PSNR) = 39.33 and structure similarity (SSIM) = 0.96 in the algorithm reconstructed image, which showed no significant difference with the simulation experiment results of PSNR = 35.19 and SSIM = 0.96 ( P < 0.05 ). In addition, the stenosis rate after interventional treatment (13.89%) was substantially lower than that before treatment (91.67%) ( P < 0.05 ). Cerebral blood flow (CBF) of the bilateral occipital lobes and cerebellum after six months of treatment was higher than that before treatment ( P < 0.05 ), and the incidence of postoperative restenosis was 11.11% (4/36). Conclusion. The combination of genetic algorithm and compressed sensing algorithm had a good effect on MRI image processing. The posterior circulation ischemia interventional stent implantation can effectively improve the stenosis of the vertebral artery and vertebral basilar artery as well as the cerebral tissue perfusion in the ischemic area, which improved the clinical symptoms substantially and reduced the probability of restenosis.
Highlights
Stroke is a common and frequently occurring disease in clinical practice, with a very high rate of disability and mortality, among which ischemic stroke accounts for about 80% [1,2,3]
Of the 36 patients treated with interventional therapy, 12 patients received stents only in the vertebral artery, 20 patients only received stents in the basilar artery, and 4 patients received stents in both the vertebral artery and the basilar artery. e stenosis rate before interventional treatment was 91.67%, which dropped to 13.89% after interventional treatment, and the difference was considerable (P < 0.05) (Table 1)
As a common and frequently occurring disease in clinical practice, ischemic stroke poses a great threat to people’s health and life, so the effective treatment of this disease has become the focus of research. ere is a certain significance of imaging technology for the evaluation of the treatment effect of stroke. erefore, magnetic resonance imaging (MRI) images processed under genetic algorithm and compressed sensing reconstruction algorithm were introduced to evaluate the improved conditions of patients and neurological function changes before and after interventional treatment
Summary
Stroke is a common and frequently occurring disease in clinical practice, with a very high rate of disability and mortality, among which ischemic stroke accounts for about 80% [1,2,3]. About 20% of ischemic stroke cases are caused by posterior circulation ischemia, namely, cerebral ischemia caused by vertebral-basilar artery stenosis, with a mortality rate of about 70% [4]. Studies revealed that early use of endovascular intervention can greatly reduce the incidence of stroke in patients with severe vertebrobasilar artery stenosis, but its safety and effectiveness have not been proven [5]. Compared with the symptoms of anterior circulation ischemia, posterior circulation ischemia has no typical clinical manifestations and imaging characteristics, which is more severe, has higher mortality and longer thrombolytic window, and is easy to cause brain damage. To protect and restore the function of Scientific Programming damaged neurons, early treatment and early intervention should be carried out for ischemic brain injury [6, 7]
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