Abstract

Objective To investigate the efficacy and safety of ALA-PDT combined with Quxietang douching in the treatment of cervical HPV infection. Methods 208 female cervical PCR-HPV positive patients were randomly divided into treatment group and control group, each group had 104 cases.The control group received 10% (ALA) in cervical for 3 hours, then red light for 30 minutes once a week, a total of 3 times.Treatment group was given 10% (ALA) in cervical for 3 hours, then red light for 30 minutes once a week, a total of 3 times, and douching vagina with Quxietang, one day at a time, stay 3 weeks.After treatment for 3 months, every month, a cervical PCR-HPV check was conducted, summarized virus removal efficiency. Results The virus removal efficiency of treatment group was 89.42%, that of the control group was 73.08%, the difference was statistically significant (χ2=7.471, P<0.05). The patients in the treatment group had light local mild erythema, swelling, burning pain, without treatment subside. Conclusion ALA-PDT combined with Quxietang douching method is efficient, with mild adverse reactions, the treatment group was better than the control group in removing cervical HPV infection and effectively eliminating the hidden trouble of cervical HPV. Key words: Humom papillmavirus; ALA-PDT; Quxietang; Cervix uteri

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