Curative effect analysis of hysteroscopy combined with laparoscopy in the diagnosis and treatment of refractory polycystic ovarian syndrome complicated with infertility

Abstract

Objective To investigate the effect and necessity of hysteroscopy combined with laparoscopy in the diagnosis and treatment of refractory polycystic ovarian syndrome complicated with infertility. Methods 80 cases of patients with polycystic ovary syndrome(PCOS)combined with infertility were randomly divided into two groups with 40 cases in each group. The testing group used hysteroscopy combined with laparoscopy in diagnosis and treatment while the laparoscopy was only used in the control group. The changes of ovary, ovarian follicles and serum hormone level of the two groups which before and after operation were compared, and the data of postoperative normal ovulation rate, pregnancy rate and abortion rate of the two groups were recorded. Results The follicle number and ovarian volume of the testing group were significantly decreased than that before treatment, and were significantly lower than that of the control group, with statistical difference(t=3.82,3.80,3.74,3.75,all P<0.05). The serum T, LH and LH/FSH of the testing group were significantly decreased than the data before surgery, and were significantly lower compared to the control group with statistical difference(t=9.32,4.06,3.80,all P<0.05). The normal ovulation rate, pregnancy rate and abortion rate of the testing group were significantly higher compared to the control group(90.0%,62.5%and 7.5%vs.72.5%,50%and 15%)χ2=4.02,4.10,3.90,all P<0.05). Conclusion Hysteroscopy combined with laparoscopy has an obvious curative effect in the diagnosis and treatment of polycystic ovary syndrome combined with infertility, which can effectively improve ovulation rate and pregnancy rate and reduce the abortion rate, is worthy of clinical application. Key words: Polycystic ovary syndrome; Sterilec(female); Hysteroscopy; Laparoscopy