Abstract
Background and aim Preterm infants are at risk for a variety of brain lesions, which can be diagnosed by cranial ultrasound imaging. Many brain damage develop within the first few weeks of birth. It is critical to diagnose brain injury as soon as possible to implement an effective preventive measures. This study aims to distinguish the relation between grades of prematurity and development and severity of intraventricular hemorrhage (IVH) in preterm neonates. Patients and Methods In this prospective cohort study 150 preterm neonates were enrolled who admitted to the Neonatal Intensive Care Unit, Faculty of Medicine, Al-Azhar University Hospital during the study period from January 1, 2023 to July 31, 2023. All the included patients underwent cranial ultrasound. Results The commonest maternal risk factor for the development of IVH among the studied preterm neonates was premature rupture of membrane, followed by preeclampsia and eclampsia. While the commonest fetal risk factors were early gestational age, low birth weight, and fetal hypoxia. Early gestational age, low birth weight, and premature rupture of membrane were shown to be significant risk factors for development of IVH among the studied preterm neonates. Multivariate logistic regression analysis shows both early gestational age and low birth weight are still significant risk factors for development of IVH. Conclusion Using trans-cranial ultrasound we found that the occurrence and severity of IVH is directly proportional with the degree of prematurity.
Published Version
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