COVID-19 disease severity and affectations in electroneuromyographic studies

Abstract

IntroductionEmerging research has highlighted COVID-19's profound impact on the nervous system, with ongoing debate regarding its severity and the emergence of peripheral neurological disorders. This study delves into the correlation between COVID-19 severity and electromyographic abnormalities in hospitalized patients, aiming to elucidate the nature and extent of neuromuscular dysfunction associated with the disease. MethodsIn a retrospective, cross-sectional, observational study, we analyzed data from 170 patients treated at the North Physical Medicine and Rehabilitation Unit between July 2020 and April 2021. Post-COVID-19 patients underwent comprehensive motor and sensory nerve conduction studies. Spearman's correlation and Kruskal–Wallis tests were used to examine the relationship between disease severity and electromyographic findings. ResultsOf the 170 patients in the study, 71.17% were male and 28.82% female, with an average age of 48 years; the subgroup of patients with severe clinical classification predominated at 68.23%. Spearman's correlation yielded values higher than 0.5 for all parameters analyzed concerning severity classification. A significant difference was found in the average of non-evoked motor and sensory nerves, motor nerves with latency, amplitude, and conduction velocity impairment, and affected muscles regarding critical classification. ConclusionOur study showed a relationship between the severity of COVID-19 and an increase in non-evoked motor and sensory nerves, impaired motor nerve latency, amplitude, and velocity, and more affected muscles, particularly in critical cases.