Abstract

The purpose of this research is to make new alloys and evaluate their corrosion behavior and biocompatibility by adding different amounts of Mo to Ni-Cr alloys (Ni-13Cr-4Mo, Ni-13Cr-6Mo, Ni-13Cr-8Mo, and Ni-13Cr-10Mo). In this research, we used incubated 6th passage human gingival fibroblast cells for the cell viability and cell adhesion experiments. The form and amount of adhesion of human gingival fibroblast cells to alloys were observed using field emission scanning electron microscopy (FE-SEM). In order to evaluate quantitative analysis of cell adhesion and corrosion behaviors, we used the AC impedance method (at 37 ± 1 ℃ in 0.9% NaCl solution) and compared the obtained results with the results of the FE-SEM. The microstructure of the Ni-13Cr-6Mo alloy had a more uniform surface than the other alloys. The Ni-13Cr-6Mo alloy demonstrated the lowest cytotoxicity in the cell viability assay, and the highest cell adhesion and corrosion resistance in an AC impedance test. We concluded that Ni-Cr-xMo alloys have better cell viability and cell adhesion and higher electrochemical impedance than Ni-Cr alloys.

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