Abstract
Background: The objective of this study was to analyze the correlation of radiation dose and Prostate-Specific Antigen (PSA) blood level following radiation therapy in prostate cancer.Methods: The study population was serial of 13 patients with histologically proven T1b-T4, any N, M0 prostate adenocarcinoma, having any Gleason score with any PSA before and after complete EBRT (external beam radiotherapy), from January 2009 to December 2010 and evaluated for PSA decrease post-EBRT.Results: Out of 13 patients, one patient received 62 Gy, one patient received 72 Gy, and 11 patients received 80 Gy. PSA blood level was decreased (median 5.4, 9.43 and 25.27, respectively) in all patients.Conclusion: This case series results were consistent with the results of previous studies that a higher radiation dose will have a higher PSA decrease with a tolerable side effect.
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