Abstract
Background: There are changes in ovarian hormones throughout the menstrual cycle which are associated with alterations in neurohumoral mechanisms that regulate cardiovascular homeostasis. Pupil limbus diameter ratio will give an idea about the status of autonomic functions. Objective: To correlate pupil to limbus diameter ratio with physiological hemodynamic parameters like blood pressure and pulse rate in different phases of menstrual cycle. Materials and methods: It was a cross-sectional study conducted among the first year and second year female MBBS students with the age of 17 – 22 years. Physiological hemodynamic parameters like pulse and blood pressure were measured in all the participants. After recording the photographs of eyes during follicular and luteal phase of menstrual cycle, it was transferred to the power point slides and the diameter was measured manually by the two-box method. Result: Pupil to limbus diameter ratio of left eye and right eye between follicular and luteal phase (p<0.05) was statistically significant. Conclusion: It is useful for detection of variations in autonomic functions during different phases of menstrual cycle in medical students, so that intervention measures can be started at the earliest which will help to prevent further complications.
Published Version
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