Correlation of early diabetic kidney disease with diabetic peripheral neuropathy

Abstract

Objective To investigate the correlation of early diabetic kidney disease (EDKD) with diabetic peripheral neuropathy (DPN). Methods A total of 543 patients with type 2 diabetic were investigated; 24 h urinary albumin quantitation greater than 30 mg while less than 300 mg and normal kidney function were the standards for diagnosis of early diabetic kidney disease; while clinical symptom and abnormal electromyogram were the standards for diagnosis of diabetic peripheral neuropathy. Patients were divided into EDKD group (233 cases) and non EDKD group (310 cases) according to being with or without EDKD; the morbidity rates of DPN of the two groups were compared. Results The prevalance of DPN in EDKD group (56.7%) was higher than that in non EDKD group (36.8%), the difference was statistical significance between the two groups (χ2=21.212, P<0.01). Conclusions EDKD may be an important factor of increasing prevalance of DPN. Key words: Early diabetic kidney disease; Diabetes mellitus; Diabetic peripheral neuropathy; Correlation