Abstract
Background and Aims : Familial hypercholesterolemia (FH) is a genetic disorder characterized by high plasma levels of low-density lipoprotein cholesterol (LDL-C) and severe cardiovascular (CV) diseases. Coronary artery calcification (CAC) assessment and arterial stiffness measured as pulse wave velocity (PWV) are accurate in CV risk assessment, but data on HeFH are lacking. Furthermore, aortic stenosis evaluated by Doppler echocardiography with markers of severity, aortic valve area (AVA) and mean gradient (MG) are still unresolved.
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