Abstract
Summary Patients with SLE suffer from accelerated atherosclerosis due to systemic inflammation. We examined subclinical coronary artery involvement in patients with systemic lupus erythematous (SLE) by contrast enhanced inversion recovery (CE-IR) coronary magnetic resonance imaging. Background Vessel wall inflammation plays a key role in the initiation and progression of atherosclerosis, from endothelial injury to remodeling and plaque formation. Cardiovascular (CV) magnetic resonance (CMR) provides noninvasive visualization and characterization of arterial remodeling both in the great vessels, and also the coronary arteries. Contrast-enhanced inversion-recovery (CEIR) prepared coronary imaging allows detection of vessel wall enhancement by visualization of contrast agent uptake. We examined subclinical coronary artery involvement in patients with systemic lupus erythematous (SLE) by contrast enhanced inversion recovery (CE-IR) coronary magnetic resonance imaging. Methods
Highlights
Vessel wall inflammation plays a key role in the initiation and progression of atherosclerosis, from endothelial injury to remodeling and plaque formation
We examined subclinical coronary artery involvement in patients with systemic lupus erythematous (SLE) by contrast enhanced inversion recovery (CE-IR) coronary magnetic resonance imaging
There was a significant increase in mean coronary Contrast-to-noise ratio (CNR) in SLE patients (SLE vs. controls: 7.7±2 vs. 3.9 ±0.9, p
Summary
Contrast enhancement imaging in coronary arteries in patients with systemic lupus erythematosus. Valentina O Puntmann1*, David D’Cruz, Peter Taylor, Tarique Hussain, Andreas Indermuehle, Britta Butzbach, Rene M Botnar, Eike Nagel. Summary Patients with SLE suffer from accelerated atherosclerosis due to systemic inflammation. We examined subclinical coronary artery involvement in patients with systemic lupus erythematous (SLE) by contrast enhanced inversion recovery (CE-IR) coronary magnetic resonance imaging
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