Abstract
Three cases are reported of glomerular nephritis in which there were other pathologic lesions similar to those reported in cases of sensitivity to sulfa drugs. In two of these streptococcic endocarditis was present on the right side of the heart. Since glomerular nephritis is considered to be the result of a sensitivity reaction, the problem of use of sulfa drugs in diseases resulting from hypersensitivity is discussed. It is pointed out that a patient who becomes sensitized to one antigen may also become sensitive to a second antigen. Because of this, sulfa drugs should be used more carefully.
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